In South Korea, ravaged by the COVID-19 virus, Dosik runs the Cactus Motel, welcoming a variety of guests. Dahyun and Youngok, a couple from the same company, are having an affair that began the year the pandemic hit. As the two share passionate moments, delivery driver Myeongsu delivers a court envelope, revealing to Dahyun that there are nine other men in Youngok's life besides him. Jinwha, the owner of a PC bang, along with his manager Gyeongjin and part-time employees Hyeongi and Yukyeong, come to the motel to sell PC bang members' personal information to China. Influencer couple Jaei and Seojun, struggling with constant filming and COVID-19 symptoms, finally realize their feelings of love. Hajeong, an unknown idol with a criminal record, accidentally infected her sick mother with COVID-19 after being released from prison. Her manager Hansol searches for a way to show Hajeong her mother's final moments.